1 Contains
| DB identifier | Type | Name |
|---|---|---|
| IPR018300 | Conserved_site | Aminotransferase, class IV, conserved site |
| Type: | Family | Name: | Branched-chain amino acid aminotransferase II |
| Description: | Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [] into subfamilies.One of these, called class-IV, currently consists of proteins of about 270 to 415 amino-acid residues that share a few regions of sequence similarity. Surprisingly, the best conserved region does not include the lysine residue to which the pyridoxal-phosphate group is known to be attached, in ilvE, but is located some 40 residues at the C terminus side of the PlP-lysine.Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE) (). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. | Short Name: | B_amino_transII |
| DB identifier | Type | Name |
|---|---|---|
| IPR018300 | Conserved_site | Aminotransferase, class IV, conserved site |
