Protein Domain : IPR014720

Type:  Domain Name:  Double-stranded RNA-binding domain
Description:  In contrast to other RNA-binding domains, the about 65 amino acids long dsRBD domain [, , ] has been found in a number of proteins that specificallyrecognise double-stranded RNAs. The dsRBD domain is also known as DSRM (Double-Stranded RNA-binding Motif). dsRBD proteins are mainly involved in posttranscriptional gene regulation, for example by preventing the expressionof proteins or by mediating RNAs localization. This domain is also found in RNA editing proteins. Interaction of the dsRBD with RNA is unlikely to involvethe recognition of specific sequences [, , ]. Nevertheless, multiple dsRBDsmay be able to act in combination to recognise the secondary structure of specific RNAs (i.e. Staufen) []. NMR analysis of the third dsRBD ofDrosophila Staufen have revealed an alpha-beta-beta-beta-alpha structure []. Short Name:  dsRBD_dom
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1 Child Features

DB identifier Type Name
IPR013810 Domain Ribosomal protein S5, N-terminal

1 Contains

DB identifier Type Name
IPR018192 Conserved_site Ribosomal protein S5, N-terminal, conserved site

4 Cross Referencess

Identifier
PF00035
PS50137
SM00358
G3DSA:3.30.160.20

1 Found In

DB identifier Type Name
IPR011907 Family Ribonuclease III

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
410705 D8RFK9 PAC:15407782 Selaginella moellendorffii 137  
431302 D8TC61 PAC:15422015 Selaginella moellendorffii 221  
412495 D8RLN4 PAC:15411696 Selaginella moellendorffii 402  
441949 D8RP21 PAC:15411754 Selaginella moellendorffii 386  
173599 D8RRN6 PAC:15415726 Selaginella moellendorffii 807  
442454 PAC:15410872 Selaginella moellendorffii 1376  
442384 D8RSZ9 PAC:15410166 Selaginella moellendorffii 817  
415236 D8RVG5 PAC:15418772 Selaginella moellendorffii 411  
141857 D8QWM6 PAC:15412778 Selaginella moellendorffii 412  
405091 D8QYC8 PAC:15410200 Selaginella moellendorffii 622  
405078 D8QYB7 PAC:15410151 Selaginella moellendorffii 509  
438470 D8QYC2 PAC:15421134 Selaginella moellendorffii 391  
71415 PAC:15423256 Selaginella moellendorffii 154  
71410 PAC:15423250 Selaginella moellendorffii 163  
64370 D8QZS0 PAC:15401962 Selaginella moellendorffii 366  
111521 D8S8M6 PAC:15411194 Selaginella moellendorffii 161  
419303 D8S8H4 PAC:15408771 Selaginella moellendorffii 1665  
432592 D8TGH0 PAC:15404384 Selaginella moellendorffii 243  
421581 D8SFQ3 PAC:15416640 Selaginella moellendorffii 871  
84784 D8R464 PAC:15419434 Selaginella moellendorffii 524  
84969 D8R3U7 PAC:15420916 Selaginella moellendorffii 357  
86110 D8R6I9 PAC:15420555 Selaginella moellendorffii 1730  
448444 D8T7D0 PAC:15405962 Selaginella moellendorffii 1719  
429802 D8T7C6 PAC:15419840 Selaginella moellendorffii 569  
75160 D8QMZ2 PAC:15410585 Selaginella moellendorffii 427  
evm.TU.contig_29936.3 PAC:16429754 Carica papaya 90  
evm.TU.contig_34457.2 PAC:16430449 Carica papaya 246  
evm.model.supercontig_10.115 PAC:16404466 Carica papaya 102  
evm.model.supercontig_117.33 PAC:16406389 Carica papaya 153  
evm.model.supercontig_119.66 PAC:16406585 Carica papaya 96  

7 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8036511
            7972084
            1357546
            7527340
            8127710
            7628456
            1438302