| Type: | Family | Name: | AdipoR/Haemolysin-III-related |
| Description: | Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus []. YOL002c (AdipoR-like receptor IZH2) from Saccharomyces cerevisiae encodes a protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolism [, ]. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adiponectin (AdipoQ) receptors (AdipoR), and hence have been named PAQR proteins []. The mammalian members include progesterone binding proteins []. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea. | Short Name: | AdipoR/HlyIII-related |
