3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0019901 | IPR015429 |
| GO:0000079 | IPR015429 |
| GO:0006355 | IPR015429 |
| Type: | Family | Name: | Cyclin C/H/T/L |
| Description: | Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles [], and regulate cyclin dependent kinases (CDKs). Cyclins, together with the p34 (cdc2) or cdk2 kinases, form the Maturation Promoting Factor (MPF). There are two main groups of cyclins, G1/S cyclins, which are essential for the control of the cell cycle at the G1/S (start) transition, and G2/M cyclins, which are essential for the control of the cell cycle at the G2/M (mitosis) transition. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed as cells exit from mitosis (at the end of the M-phase). In most species, there are multiple forms of G1 and G2 cyclins. For example, in vertebrates, there are two G2 cyclins, A and B, and at least three G1 cyclins, C, D, and E.Cyclin homologues have been found in various viruses, including Saimiriine herpesvirus 2(Herpesvirus saimiri) and Human herpesvirus 8(HHV-8) (Kaposi's sarcoma-associated herpesvirus). These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus [].The cyclins in this entry are involved in the regulation of RNA polymerase II transcription []. They include cyclins belonging to the C/H/T/L types. | Short Name: | Cyclin_C/H/T/L |
| GO Term | Gene Name |
|---|---|
| GO:0019901 | IPR015429 |
| GO:0000079 | IPR015429 |
| GO:0006355 | IPR015429 |
