Protein Domain : IPR007858

Type:  Conserved_site Name:  Dpy-30 motif
Description:  This motif is about 40 residues long and is probably formed of two alpha-helices. It is found in the Dpy-30 proteins, hence the motifs name. Dpy-30 from Caenorhabditis elegansis an essential component of dosage compensation machinery and loss of dpy-30 activity results in XX-specific lethality; in XO animals, Dpy-30 is required for developmental processes other than dosage compensation []. In yeast, the homologue of DPY-30, Saf19p, functions as part of the Set1 complex that is necessary for the methylation of histone H3 at lysine residue 4; Set1 is a key part of epigenetic developmental control []. There is also a human homologue of Dpy-30 []. This Dpy-30 region may be a dimerisation motif analogous that found in the cAMP-dependent protein kinase regulator, type II PKA, R subunit . Short Name:  Dpy-30_motif
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0 Child Features

0 Contains

1 Cross References

Identifier
PF05186

1 Found In

DB identifier Type Name
IPR012410 Family Nucleoside-diphosphate kinase-like NDK-H5

0 GO Annotation

0 Ontology Annotations

0 Parent Features

122 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
414750 D8RTU2 PAC:15419711 Selaginella moellendorffii 107  
405623 D8QZ64 PAC:15414702 Selaginella moellendorffii 137  
114076 D8SCZ1 PAC:15416210 Selaginella moellendorffii 231  
424131 D8SNX2 PAC:15422134 Selaginella moellendorffii 114  
402629 D8QMJ0 PAC:15405776 Selaginella moellendorffii 100  
60566 I0YI47 PAC:27394518 Coccomyxa subellipsoidea C-169 193  
40194 I0Z5U4 PAC:27390319 Coccomyxa subellipsoidea C-169 167  
53618 I0YW89 PAC:27388632 Coccomyxa subellipsoidea C-169 119  
50851 C1MJ88 PAC:27345386 Micromonas pusilla CCMP1545 175  
60706 C1MZE8 PAC:27344358 Micromonas pusilla CCMP1545 123  
122954 C1MLV2 PAC:27347475 Micromonas pusilla CCMP1545 353  
38543 C1MNK1 PAC:27346893 Micromonas pusilla CCMP1545 507  
57704 C1MSI5 PAC:27341860 Micromonas pusilla CCMP1545 708  
188348 C1MY51 PAC:27338680 Micromonas pusilla CCMP1545 288  
109044 C1FH75 PAC:27397596 Micromonas sp RCC299 325  
108969 C1FHZ6 PAC:27397598 Micromonas sp RCC299 368  
98338 C1EHE9 PAC:27403688 Micromonas sp RCC299 420  
56497 C1DZL5 PAC:27396533 Micromonas sp RCC299 96  
59235 C1E836 PAC:27401867 Micromonas sp RCC299 150  
101256 C1E9F5 PAC:27402146 Micromonas sp RCC299 577  
26947 A4S608 PAC:27417197 Ostreococcus lucimarinus 76  
Cre10.g427300.t1.2 Q6UBQ3 PAC:30790713 Chlamydomonas reinhardtii 738  
Cre16.g654300.t1.2 Q69B19 PAC:30778202 Chlamydomonas reinhardtii 586  
Cre06.g279100.t1.2 A8J1X7 PAC:30779379 Chlamydomonas reinhardtii 110  
Cre08.g377350.t1.1 A0A2K3DHS7 PAC:30773888 Chlamydomonas reinhardtii 1090  
Sphfalx0252s0014.1.p PAC:32600916 Sphagnum fallax 221  
Pp3c18_13110V3.1.p A0A2K1J0W8 PAC:32981626 Physcomitrium patens 260  
Pp3c18_13110V3.2.p PAC:32981627 Physcomitrium patens 196  
Pp3c21_14820V3.2.p PAC:32914561 Physcomitrium patens 264  
Pp3c21_14820V3.1.p A0A2K1IS17 PAC:32914562 Physcomitrium patens 221  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11752412
            16260194
            7588066