| Type: | Family | Name: | Pre-mRNA-processing protein PRP40 |
| Description: | This entry represent pre-mRNA-processing PRPF40 protein family, including PRP40A/PRP40B/PRP40/PRPF40A. They may be involved in pre-mRNA splicing []. In yeasts, PRP40 is associated with snRNP U1 and required for pre-spliceosome formation, which is the first step of pre-mRNA splicing []. In Arabidopsis, PRP40A/B is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes []. In humans, PRPF40A is involved in cytoskeletal organisation, cell morphology and migration []. | Short Name: | PRP40 |
