Protein Domain : IPR000812

Type:  Family Name:  Transcription factor TFIIB
Description:  In eukaryotes, transcription initiation by polymerase II is modulated by both general and specific transcription factors. The general factors (which include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIG and TFIIH) operate through common promoter elements, such as the TATA box. Transcription factor IIB (TFIIB) is of central importance in transcription of class II genes. It associates with TFIID-TFIIA bound to DNA (the DA complex) to form a ternary TFIID-IIA-IBB (DAB) complex, which is recognised by RNA polymerase II [, ]. TFIIB comprises ~315-340 residues and contains an imperfect C-terminal repeat of a 75-residue domain that may contribute to the symmetry of the folded protein. Short Name:  TFIIB
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2 Child Features

DB identifier Type Name
IPR029529 Family Transcription factor IIIB subunit Brf1
IPR023484 Family Transcription initiation factor TFIIB, archaea

3 Contains

DB identifier Type Name
IPR013150 Domain Transcription factor TFIIB, cyclin-like domain
IPR013137 Domain Zinc finger, TFIIB-type
IPR013763 Domain Cyclin-like

2 Cross Referencess

Identifier
PTHR11618
PR00685

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008270 IPR000812
GO:0006352 IPR000812
GO:0006355 IPR000812

3 Ontology Annotations

GO Term Gene Name
GO:0008270 IPR000812
GO:0006352 IPR000812
GO:0006355 IPR000812

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
412683 D8RL51 PAC:15413220 Selaginella moellendorffii 799  
444750 D8SCK8 PAC:15419011 Selaginella moellendorffii 636  
167797 D8R3Z5 PAC:15421590 Selaginella moellendorffii 342  
266576 D8QNA2 PAC:15409160 Selaginella moellendorffii 300  
410325 D8REE2 PAC:15404774 Selaginella moellendorffii 507  
evm.TU.contig_27574.1 PAC:16429513 Carica papaya 530  
evm.model.supercontig_182.4 PAC:16411581 Carica papaya 313  
evm.model.supercontig_544.3 PAC:16422467 Carica papaya 510  
evm.model.supercontig_7.51 PAC:16425213 Carica papaya 531  
evm.model.supercontig_84.29 PAC:16427309 Carica papaya 310  
30072.m000933 B9SI57 PAC:16816723 Ricinus communis 625  
30136.m001006 B9RTZ9 PAC:16819135 Ricinus communis 532  
30147.m014043 B9R917 PAC:16820057 Ricinus communis 90  
30147.m014044 B9R918 PAC:16820058 Ricinus communis 89  
30169.m006467 B9RIF2 PAC:16821267 Ricinus communis 312  
29634.m002137 B9S6G3 PAC:16804278 Ricinus communis 511  
27747.m000112 B9T586 PAC:16799069 Ricinus communis 193  
27913.m000019 B9T8A1 PAC:16799478 Ricinus communis 312  
Cucsa.127360.1 PAC:16962034 Cucumis sativus 396  
Cucsa.125440.1 PAC:16961838 Cucumis sativus 236  
Cucsa.163720.1 PAC:16965840 Cucumis sativus 631  
Cucsa.213200.1 PAC:16969456 Cucumis sativus 487  
Cucsa.269010.1 A0A0A0KYQ5 PAC:16973456 Cucumis sativus 312  
orange1.1g046187m A0A067GW19 PAC:18125060 Citrus sinensis 510  
orange1.1g023713m A0A067G8T2 PAC:18118482 Citrus sinensis 278  
orange1.1g021438m A0A067G8L1 PAC:18118481 Citrus sinensis 312  
orange1.1g025357m A0A067GBH4 PAC:18118483 Citrus sinensis 254  
orange1.1g008401m A0A067FRD7 PAC:18131799 Citrus sinensis 567  
orange1.1g009187m A0A067FIQ5 PAC:18131801 Citrus sinensis 540  
orange1.1g008455m A0A067FS52 PAC:18131800 Citrus sinensis 565  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1876184
            1949150