Protein Domain : IPR016156

Type:  Domain Name:  FAD/NAD-linked reductase, dimerisation domain
Description:  This entry represents a dimerisation domain that is usually found at the C-terminal of FAD and NAD-linked reductases. This domain has a core alpha+beta sandwich structure consisting of beta(3,4)-alpha(3). The first two domains are of the same beta/beta/alpha fold. This domain can be found in the following proteins:Glutathione reductase [].Trypanothione reductase [].Mammalian thioredoxin reductase [].Apoptosis-inducing factor (AIF), which contains a large loop insertion in this domain [].NADH peroxidase [].NADH-dependent ferredoxin reductase, BphA4 [].Putidaredoxin reductase [].Dihydrolipoamide dehydrogenase [].NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase [].The flavin-binding subunit of flavocytochrome c sulphide dehydrogenase (FCSD) [].NADH oxidase /nitrite reductase. Short Name:  FAD/NAD-linked_Rdtase_dimer
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3 Child Features

DB identifier Type Name
IPR004099 Domain Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPR015323 Domain Flavocytochrome c sulphide dehydrogenase, flavin-binding
IPR028202 Domain Reductase, C-terminal

0 Contains

1 Cross References

Identifier
SSF55424

2 Found Ins

DB identifier Type Name
IPR021179 Family Mercury(II) reductase
IPR001864 Family Trypanothione reductase

3 GO Annotations

GO Term Gene Name
GO:0016491 IPR016156
GO:0050660 IPR016156
GO:0055114 IPR016156

3 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR016156
GO:0050660 IPR016156
GO:0055114 IPR016156

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
438142 D8QUD3 PAC:15418885 Selaginella moellendorffii 485  
116004 D8SFR3 PAC:15421782 Selaginella moellendorffii 496  
445122 D8SFW3 PAC:15417233 Selaginella moellendorffii 510  
164085 D8QML3 PAC:15407427 Selaginella moellendorffii 488  
170362 D8RD19 PAC:15405237 Selaginella moellendorffii 487  
440551 D8RCG0 PAC:15405680 Selaginella moellendorffii 488  
145962 D8RCP5 PAC:15402843 Selaginella moellendorffii 433  
evm.model.supercontig_146.65 PAC:16409157 Carica papaya 510  
evm.model.supercontig_186.12 PAC:16411693 Carica papaya 478  
evm.model.supercontig_2231.1 PAC:16414030 Carica papaya 443  
evm.model.supercontig_5.56 PAC:16421506 Carica papaya 434  
evm.model.supercontig_52.87 PAC:16422114 Carica papaya 554  
evm.model.supercontig_59.122 PAC:16423130 Carica papaya 494  
evm.model.supercontig_929.4 PAC:16428688 Carica papaya 568  
29883.m001999 B9S4S9 PAC:16812086 Ricinus communis 560  
29889.m003358 B9RZW7 PAC:16812304 Ricinus communis 510  
29904.m002966 B9RWJ9 PAC:16812611 Ricinus communis 496  
29917.m001987 B9S635 PAC:16813591 Ricinus communis 478  
30190.m011270 B9RCH2 PAC:16823627 Ricinus communis 493  
40016.m000026 B9TP24 PAC:16827274 Ricinus communis 85  
27675.m000082 B9T979 PAC:16798939 Ricinus communis 456  
Cucsa.316060.1 A0A0A0KG56 PAC:16977100 Cucumis sativus 562  
Cucsa.388700.1 A0A0A0K8Q7 PAC:16982887 Cucumis sativus 551  
Cucsa.388700.2 A0A0A0K8Q7 PAC:16982888 Cucumis sativus 551  
Cucsa.011450.1 PAC:16951425 Cucumis sativus 480  
Cucsa.083200.1 PAC:16956397 Cucumis sativus 434  
Cucsa.135160.1 PAC:16962878 Cucumis sativus 510  
Cucsa.074510.1 A0A0A0L7V7 PAC:16955658 Cucumis sativus 552  
Cucsa.240950.1 A0A0A0LGL9 PAC:16970960 Cucumis sativus 434  
Cucsa.252370.1 PAC:16971934 Cucumis sativus 506  

10 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11090282
            12390015
            7766608
            8805537
            7939681
            8771196
            9546215
            11481439
            12198487
            15095867