Protein Domain : IPR001078

Type:  Domain Name:  2-oxoacid dehydrogenase acyltransferase, catalytic domain
Description:  This domain is found in the lipoamide acyltransferase component of the branched-chain alpha-keto acid dehydrogenase complex , which catalyses the overall conversion of alpha-keto acids to acyl-CoA and carbon dioxide []. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamideacyltransferase (E2) and lipoamide dehydrogenase (E3). The domain is also found in the dihydrolipoamide succinyltransferase component of the 2-oxoglutarate dehydrogenase complex . These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain. Short Name:  2-oxoacid_DH_actylTfrase
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0 Child Features

0 Contains

1 Cross References

Identifier
PF00198

5 Found Ins

DB identifier Type Name
IPR006255 Family Dihydrolipoamide succinyltransferase
IPR006257 Family Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
IPR006256 Family Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex
IPR015761 Family Lipoamide Acyltransferase
IPR014276 Family 2-oxoglutarate dehydrogenase, E2 component

2 GO Annotations

GO Term Gene Name
GO:0016746 IPR001078
GO:0008152 IPR001078

2 Ontology Annotations

GO Term Gene Name
GO:0016746 IPR001078
GO:0008152 IPR001078

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
94277 D8RIN1 PAC:15422739 Selaginella moellendorffii 446  
99356 D8RQU8 PAC:15415855 Selaginella moellendorffii 590  
82229 D8R0R1 PAC:15409633 Selaginella moellendorffii 431  
163943 D8QQW2 PAC:15411464 Selaginella moellendorffii 362  
227145 D8QPY3 PAC:15402432 Selaginella moellendorffii 501  
evm.model.supercontig_106.32 PAC:16405196 Carica papaya 545  
evm.model.supercontig_1199.1 PAC:16406631 Carica papaya 374  
evm.model.supercontig_128.57 PAC:16407483 Carica papaya 609  
evm.model.supercontig_3.118 PAC:16416389 Carica papaya 393  
evm.model.supercontig_50.171 PAC:16421634 Carica papaya 501  
evm.model.supercontig_66.53 PAC:16424618 Carica papaya 474  
29706.m001326 B9S5V2 PAC:16806339 Ricinus communis 543  
29726.m004073 B9RT82 PAC:16806784 Ricinus communis 504  
29728.m000838 B9SLH2 PAC:16806908 Ricinus communis 473  
30061.m000282 B9SL87 PAC:16816334 Ricinus communis 633  
30064.m000498 B9SVA1 PAC:16816429 Ricinus communis 469  
31488.m000025 B9TKI7 PAC:16825058 Ricinus communis 113  
32909.m000024 PAC:16825614 Ricinus communis 223  
55024.m000017 B9TM06 PAC:16828769 Ricinus communis 331  
28883.m000717 B9ST02 PAC:16801917 Ricinus communis 483  
Cucsa.341030.1 PAC:16979158 Cucumis sativus 571  
Cucsa.341030.10 A0A0A0LFR2 PAC:16979159 Cucumis sativus 538  
Cucsa.341030.11 A0A0A0LFR2 PAC:16979160 Cucumis sativus 538  
Cucsa.341030.13 A0A0A0LFR2 PAC:16979162 Cucumis sativus 538  
Cucsa.341030.2 PAC:16979163 Cucumis sativus 571  
Cucsa.341030.7 A0A0A0LFR2 PAC:16979168 Cucumis sativus 538  
Cucsa.007330.2 PAC:16951225 Cucumis sativus 465  
Cucsa.007330.1 PAC:16951224 Cucumis sativus 469  
Cucsa.163200.2 PAC:16965793 Cucumis sativus 637  
Cucsa.240920.1 PAC:16970955 Cucumis sativus 464  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8487300