| Type: | Family | Name: | Prohibitin |
| Description: | Genes that negatively regulate proliferation inside the cell are of considerable interest because of the implications in processes such as development and cancer []. Prohibitin, a novel cytoplasmic anti-proliferative protein widely expressed in a variety of tissues, inhibitsDNA synthesis. Studies have suggested that prohibitin may be a suppressor gene and is associated with tumour development and/or progression of atleast some breast cancers []. Sequence comparisons suggest that the prohibitin gene is an analogue of Cc, a Drosophila melanogastergene that is vital for normal development []. | Short Name: | Prohibitin |
