Protein Domain : IPR011289

Type:  Family Name:  Fructose-1,6-bisphosphate aldolase, class 2
Description:  Fructose-1,6-bisphosphate (FBP) aldolases reversibly cleave FBP to two triose phosphates, glycerone phophate and D-glyceraldehyde 3-phosphate. They play a key role in both glycolysis (FBP cleavage) and gluconeogenesis (FBP synthesis). These enzymes can be divide into two classes based on their mode of catalysis. Class I FBP aldolases form a Schiff-base intermediate between glycerone phophate and an active site lysine residue, while the class II enzymes use a divalent cation such as Zn(2+) for catalysis [].This entry represents class II FBP aldolases found in Gram-positive bacteria, a variety of Gram-negative baceria, and amitochondriate protists. These enzymes are homotetramers where each momomer forms a TIM barrel fold []. Short Name:  Fruc_bis_ald_class-2
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0 Child Features

0 Contains

1 Cross References

Identifier
TIGR01859

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004332 IPR011289
GO:0008270 IPR011289
GO:0006096 IPR011289
GO:0030388 IPR011289

4 Ontology Annotations

GO Term Gene Name
GO:0004332 IPR011289
GO:0008270 IPR011289
GO:0006096 IPR011289
GO:0030388 IPR011289

1 Parent Features

DB identifier Type Name
IPR000771 Family Ketose-bisphosphate aldolase, class-II

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s32_560V3.1.p PAC:32948367 Physcomitrium patens 2042  
Pp3s34_503V3.1.p PAC:32948279 Physcomitrium patens 279  
Brdisv1pangenome1012271m.p PAC:33656340 Brachypodium distachyon Pangenome 332  
Brdisv1BdTR12c1043800m.p PAC:34404445 Brachypodium distachyon BdTR12c 556  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1412694
            14699122