| Type: | Domain | Name: | Staphostatin A/B |
| Description: | Staphostatin A (SAV1910, SA1726) and B (SspC) are cysteine protease inhibitors belonging to MEROPS inhibitor families I57 and I58 (clan IK). They have a beta-barrel topology that act as specific inhibitors of staphopains, the major secreted cysteine proteases of Staphylococcus aureus[, ]. These inhibitors compete with substrate for binding at the active site of the staphopain, acting to protect intracellular proteins against proteolytic damage by prematurely folded and activated staphopains []. They are also involved in growth capacity, viability and bacterial morphology. | Short Name: | Staphostatin_A/B |
