Protein Domain : IPR008048

Type:  Family Name:  DNA replication licensing factor Mcm
Description:  The MCM2-7 complex consists of six closely related proteins that are highly conserved throughout the eukaryotic kingdom. In eukaryotes, Mcm5 is a component of the MCM2-7 complex (MCM complex), which consists of six sequence-related AAA + type ATPases/helicases that form a hetero-hexameric ring []. MCM2-7 complex is part of the pre-replication complex (pre-RC). In G1 phase, inactive MCM2-7 complex is loaded onto origins of DNA replication [, , ]. During G1-S phase, MCM2-7 complex is activated to unwind the double stranded DNA and plays an important role in DNA replication forks elongation [].The components of the MCM2-7 complex are: . DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, DNA replication licensing factor MCM5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM7, Short Name:  MCM5
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0 Child Features

2 Contains

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold
IPR018525 Conserved_site Mini-chromosome maintenance, conserved site

1 Cross References

Identifier
PR01661

0 Found In

7 GO Annotations

GO Term Gene Name
GO:0003678 IPR008048
GO:0003682 IPR008048
GO:0003688 IPR008048
GO:0005524 IPR008048
GO:0006270 IPR008048
GO:0005634 IPR008048
GO:0042555 IPR008048

7 Ontology Annotations

GO Term Gene Name
GO:0003678 IPR008048
GO:0003682 IPR008048
GO:0003688 IPR008048
GO:0005524 IPR008048
GO:0006270 IPR008048
GO:0005634 IPR008048
GO:0042555 IPR008048

0 Parent Features

279 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
88878 D8R9T1 PAC:15409562 Selaginella moellendorffii 727  
evm.model.supercontig_397.6 PAC:16419162 Carica papaya 948  
29737.m001249 B9SC12 PAC:16807267 Ricinus communis 723  
Cucsa.132650.1 A0A0A0LL55 PAC:16962590 Cucumis sativus 735  
orange1.1g004862m A0A067EW69 PAC:18121986 Citrus sinensis 726  
AT2G07690.2 F4INF9 PAC:19640040 Arabidopsis thaliana 725  
AT2G07690.1 O80786 PAC:19640039 Arabidopsis thaliana 727  
Thhalv10022493m V4N196 PAC:20190032 Eutrema salsugineum 727  
Ciclev10007588m V4UL71 PAC:20793130 Citrus clementina 726  
Lus10040017 PAC:23173393 Linum usitatissimum 690  
Lus10019592 PAC:23142562 Linum usitatissimum 693  
Potri.006G188700.1 A0A2K2A4G9 PAC:27006864 Populus trichocarpa 726  
Potri.018G112800.1 A0A2K1WZE5 PAC:27009878 Populus trichocarpa 726  
Gorai.013G218100.1 A0A0D2W8B2 PAC:26788109 Gossypium raimondii 734  
52389 I0Z7F9 PAC:27393506 Coccomyxa subellipsoidea C-169 739  
43598 C1N9Q3 PAC:27343889 Micromonas pusilla CCMP1545 748  
84917 C1ED12 PAC:27401261 Micromonas sp RCC299 770  
37286 A4RVG5 PAC:27415709 Ostreococcus lucimarinus 709  
Thecc1EG047088t1 A0A061GJP7 PAC:27429698 Theobroma cacao 734  
Migut.K00361.1.p A0A022QW43 PAC:28938132 Mimulus guttatus 733  
Araha.15313s0001.1.p PAC:28837876 Arabidopsis halleri 413  
Cagra.4072s0001.1.p PAC:28913010 Capsella grandiflora 222  
Glyma.13G156400.1.p I1LZM7 PAC:30506058 Glycine max 732  
Glyma.17G104000.2.p A0A0R0FB82 PAC:30481401 Glycine max 727  
Glyma.17G104000.1.p I1MTX9 PAC:30481400 Glycine max 732  
Brara.C04051.1.p A0A398AA72 PAC:30617643 Brassica rapa FPsc 727  
Bostr.24399s0001.1.p PAC:30659013 Boechera stricta 727  
Cre01.g023150.t1.2 A0A2K3E6D5 PAC:30789174 Chlamydomonas reinhardtii 751  
Medtr4g116870.1 A0A072UR54 PAC:31113586 Medicago truncatula 733  
SapurV1A.0626s0090.1.p PAC:31426028 Salix purpurea 729  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19896182
            19910535
            22841721
            17506634