Type: | Domain | Name: | Sec7 domain, alpha orthogonal bundle |
Description: | The Sec7 domain was named after the first protein found to contain such a region []. It has been shown to be linked with guanine nucleotide exchange function [, ].The 3D structure of the domain displays several alpha-helices []. It was found to be associated with other domains involved in guanine nucleotide exchange (e.g., CDC25, Dbl) in mammalian factors [].This entry represents the alpha orthogonal structural domain which is found in the C terminus of the Sec7 domain, . | Short Name: | Sec7_alpha_orthog |