Protein Domain : IPR006157

Type:  Domain Name:  Dihydroneopterin aldolase/epimerase domain
Description:  Dihydroneopterin aldolase catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. In the opportunistic pathogen Pneumocystis carinii, dihydroneopterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid synthesis protein (Fas). This region encompasses two domains, FasA and FasB, which are 27% amino acid identical. FasA and FasB also share significant amino acid sequence similarity with bacterial dihydroneopterin aldolases.This region consists of two tandem sequences each homologous to folB and which form tetramers []. Short Name:  FolB_dom
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0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF02152
SM00905
TIGR00526

1 Found In

DB identifier Type Name
IPR016261 Family Folic acid synthesis protein FOL1

2 GO Annotations

GO Term Gene Name
GO:0004150 IPR006157
GO:0006760 IPR006157

2 Ontology Annotations

GO Term Gene Name
GO:0004150 IPR006157
GO:0006760 IPR006157

0 Parent Features

686 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
84592 D8R3P1 PAC:15417923 Selaginella moellendorffii 128  
evm.model.supercontig_104.4 PAC:16405045 Carica papaya 131  
29333.m001071 B9SDL5 PAC:16802685 Ricinus communis 133  
Cucsa.093790.4 A0A0A0KU85 PAC:16957651 Cucumis sativus 151  
Cucsa.093790.2 A0A0A0KU85 PAC:16957649 Cucumis sativus 151  
Cucsa.093790.3 A0A0A0KU85 PAC:16957650 Cucumis sativus 151  
Cucsa.093790.1 A0A0A0KU85 PAC:16957648 Cucumis sativus 151  
orange1.1g032783m A0A067DC52 PAC:18129867 Citrus sinensis 134  
orange1.1g032753m A0A067DC52 PAC:18129868 Citrus sinensis 134  
AT5G62980.1 Q9FM54 PAC:19667800 Arabidopsis thaliana 131  
AT3G11750.1 Q9SF23 PAC:19660304 Arabidopsis thaliana 146  
AT3G21730.2 A0A7G2EK75 PAC:19664291 Arabidopsis thaliana 156  
Thhalv10021697m V4M8Z2 PAC:20182340 Eutrema salsugineum 152  
Thhalv10005125m V4MJR7 PAC:20199232 Eutrema salsugineum 127  
Ciclev10013089m V4SRE5 PAC:20796935 Citrus clementina 134  
Lus10013600 PAC:23168741 Linum usitatissimum 134  
Lus10021252 PAC:23178294 Linum usitatissimum 134  
Potri.016G067200.2 B9III2 PAC:27012672 Populus trichocarpa 133  
Potri.016G067200.1 B9III2 PAC:27012673 Populus trichocarpa 133  
Gorai.002G153400.1 A0A0D2R6L3 PAC:26794041 Gossypium raimondii 135  
Gorai.012G141600.1 A0A0D2V5C4 PAC:26826075 Gossypium raimondii 140  
Gorai.006G076900.1 A0A0D2NJA3 PAC:26830677 Gossypium raimondii 85  
57423 I0YR57 PAC:27387835 Coccomyxa subellipsoidea C-169 149  
137779 C1MNT6 PAC:27347797 Micromonas pusilla CCMP1545 118  
33546 A4S2S0 PAC:27413893 Ostreococcus lucimarinus 114  
Thecc1EG023087t2 A0A061EV37 PAC:27421090 Theobroma cacao 107  
Thecc1EG023087t1 A0A061EVS6 PAC:27421089 Theobroma cacao 142  
Migut.L01853.2.p PAC:28935668 Mimulus guttatus 123  
Migut.L01853.3.p A0A022REA8 PAC:28935666 Mimulus guttatus 129  
Migut.L01853.1.p A0A022REA8 PAC:28935667 Mimulus guttatus 129  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9709001