Type: | Family | Name: | Dihydroneopterin aldolase |
Description: | Dihydroneopterin aldolase catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway oftetrahydrofolate. The enzyme form a homo-octamers. Aldolase can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerizationof carbon 2' of dihydroneopterin and dihydromonapterin at appreciable velocity []. | Short Name: | Dihydroneopterin_aldolase |