Type: | Family | Name: | Gamma interferon inducible lysosomal thiol reductase GILT |
Description: | This family includes the two characterised human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences [, ]. It also contains several other eukaryotic putative proteins with similarity to GILT []. Thealigned region contains three conserved cysteine residues. In addition, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulphide bond reduction. | Short Name: | Interferon-induced_GILT |