Protein Domain : IPR010971

Type:  Family Name:  Ubiquinone biosynthesis hydroxylase UbiH/COQ6
Description:  This entry represents a family of FAD-dependent hydroxylases (monooxygenases), which are all believed to act in the aerobic ubiquinone biosynthesis pathway []. In Escherichia coli, three enzyme activities have been described: UbiI, UbiH and UbiF []. UbiH and UbiF are similar to one another and form the basis of this subfamily. UbiI (also known as visC) [] is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (also known as visB) []. Several other species appear to have three homologues in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homologue in this subfamily (COQ6, []) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. Short Name:  UbiH/COQ6
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2 Child Features

DB identifier Type Name
IPR000689 Family Ubiquinone biosynthesis monooxygenase COQ6
IPR011295 Family 2-polyprenyl-6-methoxyphenol 4-hydroxylase

2 Contains

DB identifier Type Name
IPR006076 Domain FAD dependent oxidoreductase
IPR018168 Conserved_site Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site

1 Cross References

Identifier
TIGR01988

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016709 IPR010971
GO:0050660 IPR010971
GO:0006744 IPR010971
GO:0055114 IPR010971

4 Ontology Annotations

GO Term Gene Name
GO:0016709 IPR010971
GO:0050660 IPR010971
GO:0006744 IPR010971
GO:0055114 IPR010971

0 Parent Features

561 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
230657 D8R392 PAC:15415469 Selaginella moellendorffii 440  
evm.model.supercontig_59.105 PAC:16423111 Carica papaya 574  
29904.m002977 B9RWL0 PAC:16812622 Ricinus communis 515  
52958.m000013 B9TLA2 PAC:16828580 Ricinus communis 342  
Cucsa.107050.2 PAC:16959550 Cucumis sativus 510  
Cucsa.107050.1 PAC:16959549 Cucumis sativus 512  
orange1.1g010200m PAC:18119310 Citrus sinensis 515  
orange1.1g010225m PAC:18119311 Citrus sinensis 514  
orange1.1g013000m PAC:18119312 Citrus sinensis 451  
orange1.1g013625m PAC:18119313 Citrus sinensis 439  
AT3G24200.2 F4J6I6 PAC:19664957 Arabidopsis thaliana 507  
AT3G24200.1 F4J6I5 PAC:19664958 Arabidopsis thaliana 505  
Thhalv10002522m V4MXN3 PAC:20196801 Eutrema salsugineum 460  
Ciclev10004802m V4RIJ6 PAC:20790797 Citrus clementina 504  
Ciclev10004754m V4S0S2 PAC:20790796 Citrus clementina 515  
Lus10000752 PAC:23148779 Linum usitatissimum 1188  
Lus10011742 PAC:23165927 Linum usitatissimum 626  
Potri.001G051200.1 B9GMF8 PAC:27045586 Populus trichocarpa 513  
Potri.001G051200.2 U5GPF2 PAC:27045587 Populus trichocarpa 447  
Gorai.006G220300.2 A0A0D2QER5 PAC:26831349 Gossypium raimondii 503  
Gorai.006G220300.1 A0A0D2S0M2 PAC:26831348 Gossypium raimondii 510  
36009 I0Z1W5 PAC:27387519 Coccomyxa subellipsoidea C-169 417  
83519 C1E9Y3 PAC:27404375 Micromonas sp RCC299 490  
88383 A4S3G5 PAC:27416352 Ostreococcus lucimarinus 511  
Thecc1EG020380t2 A0A061EJZ2 PAC:27455154 Theobroma cacao 504  
Thecc1EG020380t1 A0A061EJZ2 PAC:27455153 Theobroma cacao 504  
Migut.G00632.1.p A0A022QSL4 PAC:28942513 Mimulus guttatus 497  
Araha.11474s0002.1.p PAC:28863367 Arabidopsis halleri 505  
Cagra.0026s0032.1.p PAC:28919720 Capsella grandiflora 506  
Glyma.08G345200.1.p K7LAM2 PAC:30537820 Glycine max 510  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12721307
            11583838
            23709220
            1339425