Protein Domain : IPR013209

Type:  Domain Name:  Lipin/Ned1/Smp2 (LNS2)
Description:  This domain is found in lipins and lipin homologues from Saccharomyces cerevisiae (Smp2) and from Schizosaccharomyces pombe (Ned1) []. Smp2 (also known as PAH1) is involved in plasmid maintenance and respiration [] and has been identified as a Mg2+-dependent phosphatidate phosphatase () that contains a haloacid dehalogenase (HAD)-like domain []. Lipin proteins are phosphatidate phosphatases which catalyse the dephosphorylation of phosphatidic acid to diacylglycerol, the penultimate step in triacylglycerol synthesis []. They are involved in adipose tissue development and insulin resistance []. Short Name:  LNS2
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0 Child Features

0 Contains

1 Cross References

Identifier
PF08235

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR031315 Domain LNS2/PITP

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
115253 D8SER1 PAC:15420593 Selaginella moellendorffii 168  
4915 D8SHM5 PAC:15419577 Selaginella moellendorffii 186  
evm.model.supercontig_114.16 PAC:16406105 Carica papaya 849  
evm.model.supercontig_49.6 PAC:16421130 Carica papaya 881  
30170.m013896 B9R7E6 PAC:16821740 Ricinus communis 1143  
30170.m013897 B9R7E7 PAC:16821741 Ricinus communis 1078  
Cucsa.065810.1 PAC:16955104 Cucumis sativus 787  
Cucsa.232780.1 PAC:16970297 Cucumis sativus 1027  
Cucsa.307480.1 A0A0A0LA92 PAC:16976215 Cucumis sativus 914  
Cucsa.307480.2 A0A0A0LA92 PAC:16976216 Cucumis sativus 914  
orange1.1g002531m A0A067E444 PAC:18099134 Citrus sinensis 912  
orange1.1g002528m A0A067E444 PAC:18099135 Citrus sinensis 912  
orange1.1g002532m A0A067E444 PAC:18099133 Citrus sinensis 912  
orange1.1g002634m A0A067E7I6 PAC:18099136 Citrus sinensis 898  
orange1.1g001520m PAC:18092400 Citrus sinensis 1061  
orange1.1g002573m PAC:18092403 Citrus sinensis 906  
orange1.1g001551m PAC:18092401 Citrus sinensis 1055  
orange1.1g001552m PAC:18092402 Citrus sinensis 1055  
AT5G42870.2 F4K347 PAC:19669689 Arabidopsis thaliana 925  
AT5G42870.1 Q9FMN2 PAC:19669688 Arabidopsis thaliana 930  
AT3G09560.3 Q9SF47 PAC:19662442 Arabidopsis thaliana 904  
AT3G09560.2 Q9SF47 PAC:19662441 Arabidopsis thaliana 904  
AT3G09560.1 Q9SF47 PAC:19662440 Arabidopsis thaliana 904  
Thhalv10020030m V4M9Q1 PAC:20181751 Eutrema salsugineum 878  
Thhalv10003142m V4NFA0 PAC:20208058 Eutrema salsugineum 921  
Thhalv10003158m V4L393 PAC:20208059 Eutrema salsugineum 731  
Ciclev10000118m V4SJW5 PAC:20787676 Citrus clementina 1055  
Lus10025284 PAC:23157380 Linum usitatissimum 872  
Lus10009064 PAC:23172395 Linum usitatissimum 860  
Lus10021733 PAC:23154331 Linum usitatissimum 1012  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11792863
            12376568
            16467296
            23603613