Protein Domain : IPR012981

Type:  Family Name:  PIH1 family
Description:  Proteins in this family contain PIH1 domains. This family consists of the kintoun, Saccharomyces cerevisiae PIH1 (protein interacting with Hsp90 1, also known as Nop17) and PIH1 domain-containing proteins. Kintoun is required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. It involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment [].PIH1 is a component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1), which interacts with Hsp90 to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II []. PTH1 is also involved in pre-rRNA processing and required for the NOP58-snoRNA interaction []. Short Name:  PIH1
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1 Child Features

DB identifier Type Name
IPR026697 Family PIH1 domain-containing protein 3

0 Contains

2 Cross Referencess

Identifier
PTHR22997
PF08190

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

78 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
406682 D8R143 PAC:15417677 Selaginella moellendorffii 341  
41800 I0YYZ3 PAC:27386898 Coccomyxa subellipsoidea C-169 341  
125555 C1N306 PAC:27349192 Micromonas pusilla CCMP1545 206  
130534 C1N7E8 PAC:27348506 Micromonas pusilla CCMP1545 111  
164352 PAC:27348803 Micromonas pusilla CCMP1545 246  
193077 C1MMH5 PAC:27347254 Micromonas pusilla CCMP1545 541  
56863 C1MNC2 PAC:27347636 Micromonas pusilla CCMP1545 424  
63813 C1EFJ6 PAC:27402774 Micromonas sp RCC299 591  
108029 C1E591 PAC:27400549 Micromonas sp RCC299 188  
58271 C1E5D0 PAC:27395668 Micromonas sp RCC299 412  
50263 C1E684 PAC:27395790 Micromonas sp RCC299 607  
25905 A4SBI8 PAC:27420267 Ostreococcus lucimarinus 396  
Cre10.g467050.t1.2 A0A2K3DCB0 PAC:30790213 Chlamydomonas reinhardtii 433  
Cre07.g335800.t1.1 A0A2K3DK73 PAC:30774645 Chlamydomonas reinhardtii 188  
Cre09.g411450.t1.2 A0A2K3DFM0 PAC:30781292 Chlamydomonas reinhardtii 675  
Sphfalx0076s0013.1.p PAC:32608857 Sphagnum fallax 178  
Sphfalx0022s0129.1.p PAC:32616031 Sphagnum fallax 170  
Pp3c17_1080V3.1.p A0A2K1J2C2 PAC:32905501 Physcomitrium patens 97  
Pp3c22_15060V3.1.p A0A2K1INK2 PAC:32905228 Physcomitrium patens 185  
Pp3c22_15060V3.2.p PAC:32905229 Physcomitrium patens 172  
Pp3c24_18590V3.1.p A0A2K1IHA5 PAC:32910515 Physcomitrium patens 185  
Pp3c3_32320V3.1.p A0A2K1KWX9 PAC:32942010 Physcomitrium patens 532  
Mapoly0066s0043.1.p A0A2R6WQG6 PAC:33005928 Marchantia polymorpha 166  
Mapoly0081s0070.2.p A0A2R6WKG3 PAC:33018985 Marchantia polymorpha 313  
Mapoly0081s0070.1.p A0A2R6WKF6 PAC:33018984 Marchantia polymorpha 368  
Mapoly0005s0079.1.p A0A2R6XQP1 PAC:33003470 Marchantia polymorpha 458  
Mapoly0005s0079.2.p A0A2R6XQP1 PAC:33003471 Marchantia polymorpha 458  
Dusal.0096s00020.1.p PAC:33195843 Dunaliella salina 749  
Dusal.0905s00002.1.p PAC:33194886 Dunaliella salina 447  
Dusal.0548s00006.1.p PAC:33187564 Dunaliella salina 393  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15670595
            18268103
            19052621