| Type: | Domain | Name: | Flavodoxin-like fold |
| Description: | This entry represents a domain with a flavodoxin-like fold.Proteins with this domain include bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) . These enzymes catalyse the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species []. This enzyme uses a FAD cofactor. The equation for this reaction is NAD(P)H + acceptor = NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy []. This domain is also found in acyl carrier protein phosphodiesterase . This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP []. | Short Name: | Flavodoxin_fold |
