| Type: | Domain | Name: | BCNT-C domain |
| Description: | Vertebrate BCNT (named after Bucentaur) protein is found in the nucleus and cytosol. Gene duplication of the ancestral BCNT gene leads to the h-type BCNTor craniofacial development protein 1 (CFDP1) gene and the ruminant-specific p97BCNT or craniofacial development protein 2 (CFDP2) gene. The h-type BCNTproteins contain a highly conserved 82-amino acid region at the C terminus (BCNT-C) that is not present in p97BCNT. Instead ruminant p97BCNT contains aregion derived from the endonuclease domain of a retrotransposable element RTE-1 [, ].In addition to h-type BCNT proteins, a BCNT-C domain is also found in Drosophila YETI, a protein that binds to a microtubule-based motorkinesin-1, and the yeast SWR1-complex protein 5 (SWC5) or AOR1 (actin overexpression resistant 1), a component of the SWR1 chromatin remodelingcomplex [, ].The entry represents the entire BCNT-C domain. | Short Name: | BCNT-C |
