4 GO Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003713 | IPR025785 |
| GO:0046975 | IPR025785 |
| GO:0010452 | IPR025785 |
| GO:0018022 | IPR025785 |
4 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0003713 | IPR025785 |
| GO:0046975 | IPR025785 |
| GO:0010452 | IPR025785 |
| GO:0018022 | IPR025785 |
| Type: | Family | Name: | Histone-lysine N-methyltransferase, SETD3 |
| Description: | Members from this family methylate 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This enzyme may act as a regulator of apoptosis, possibly by regulating apoptosis related-target genes [].Methyltransferases (EC 2.1.1.-) constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl L-methionine (SAM or AdoMet) to a nucleophilic acceptor such as oxygen leading to S-adenosyl-L-homocysteine (AdoHcy) and a methylated molecule [, , ]. All these enzymes have in common a conserved region of about 130 amino acid residues that allow them to bind SAM []. The substrates that are methylated by these enzymes cover virtually every kind of biomolecules ranging from small molecules, to lipids, proteins and nucleic acids [, , ]. Methyltransferase are therefore involved in many essential cellular processes including biosynthesis, signal transduction, protein repair, chromatin regulation and gene silencing [, , ]. More than 230 families of methyltransferases have been described so far, of which more than 220 use SAM as the methyl donor. | Short Name: | Hist-Lys_N-MeTrfase_SETD3 |
| GO Term | Gene Name |
|---|---|
| GO:0003713 | IPR025785 |
| GO:0046975 | IPR025785 |
| GO:0010452 | IPR025785 |
| GO:0018022 | IPR025785 |
| GO Term | Gene Name |
|---|---|
| GO:0003713 | IPR025785 |
| GO:0046975 | IPR025785 |
| GO:0010452 | IPR025785 |
| GO:0018022 | IPR025785 |
