Protein Domain : IPR013571

Type:  Domain Name:  Transcription regulator QacR, C-terminal
Description:  This entry represents the C-terminal domain found in the multidrug-binding transcription regulator QacR () from Staphylococcus aureus, which is a member of the TetR (tetracycline-resistance) transcriptional regulator family of proteins. QacR is able to bind various environmental agents, which include a number of cationic lipophilic compounds, and thus regulate the transcription of QacA (), a multidrug efflux pump []. The C-terminal region of QacR contains a multifaceted, expansive drug-binding pocket, which is composed of several separate, but linked, binding sites []. The C-terminal domains of QacR and TetR share a multi-helical, interlocking structure. Short Name:  Tscrpt_reg_QacR_C
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0 Child Features

0 Contains

1 Cross References

Identifier
PF08360

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003700 IPR013571
GO:0045892 IPR013571

2 Ontology Annotations

GO Term Gene Name
GO:0003700 IPR013571
GO:0045892 IPR013571

1 Parent Features

DB identifier Type Name
IPR011075 Domain Tetracycline transcriptional regulator, TetR-related, C-terminal

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11739955
            9660841