Type: | Domain | Name: | Ephrin receptor, transmembrane domain |
Description: | This entry represents the left-handed dimer transmembrane domain of Ephrin receptors. This domain oligomerises and is important for the active signalling process [].Proteins containing this domain include the ephrin type-A and type-B receptors. Ephrin receptors (Ephs) are a group of receptor tyrosine kinases that are activated in response to binding ephrin ligands residing on adjacent cells []. This binding leads to contact-dependent bidirectional signaling into neighbouring cells []. | Short Name: | Eph_TM |