| Type: | Family | Name: | Glycoside hydrolase, family 59 |
| Description: | O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Glycoside hydrolase family 59 comprises enzymes with only one known activity; galactocerebrosidase ().Globoid cell leukodystrophy (Krabbe disease) is a severe, autosomal recessive disorder that results from deficiency of galactocerebrosidase(GALC) activity [, , ]. GALC is responsible for the lysosomal catabolism ofcertain galactolipids, including galactosylceramide and psychosine []. | Short Name: | Glyco_hydro_59 |
