Protein Domain : IPR013790

Type:  Family Name:  Dwarfin
Description:  This family of proteins was first identified in Caenorhabditis elegans. Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth []. The dwarfin family also includes the Drosophila protein MAD that is required for the function of decapentaplegic (DPP) and may play a role in DPP signalling. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Dpp []. Short Name:  Dwarfin

0 Child Features

2 Contains

DB identifier Type Name
IPR013019 Domain MAD homology, MH1
IPR001132 Domain SMAD domain, Dwarfin-type

1 Cross References

Identifier
PTHR13703

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0006355 IPR013790
GO:0005622 IPR013790

2 Ontology Annotations

GO Term Gene Name
GO:0006355 IPR013790
GO:0005622 IPR013790

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9230443
            8799132