3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008270 | IPR001018 |
| GO:0008800 | IPR001018 |
| GO:0017001 | IPR001018 |
| Type: | Conserved_site | Name: | Beta-lactamase, class-B, conserved site |
| Description: | Synonym(s): Penicillinase, Cephalosporinase Beta-lactamases () are enzymes which catalyse the hydrolysis of an amide bond in the beta-lactam ring of antibiotics belonging to the penicillin/cephalosporin family. The class B enzymes are zinc containing proteins whilst class A, C and D enzymes are serine hydrolases.Class B beta-lactamases have been described in several Gram-negative bacterial species; they seem to share the characteristic of being able to hydrolyse carbapenem compounds, new beta-lactam antibiotics of greattherapeutic potential.The conserved regions in the sequence of known class B beta-lactamases are centred on residues known to be involved in binding the zinc ion essentialfor the enzymes catalytic activity [, ]. | Short Name: | Beta-lactamase_class-B_CS |
| GO Term | Gene Name |
|---|---|
| GO:0008270 | IPR001018 |
| GO:0008800 | IPR001018 |
| GO:0017001 | IPR001018 |
