Protein Domain : IPR015344

Type:  Domain Name:  Vibrio cholerae neuraminidase, lectin-like domain
Description:  These lectin-like domains is are found in Vibrio cholerae neuraminidase (VCNA). This enzyme plays a significant role in the pathogenesis of cholera by removing sialic acid from higher order gangliosides to unmask GM1, the receptor for cholera toxin. The domains flank a central beta-propeller catalytic domain. They are thought to be involved in binding sialic acid, helping to target the enzyme to sialic acid-rich environments and thereby enhancing its catalytic efficiency []. Short Name:  VCNA_lectin-like_dom
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0 Child Features

0 Contains

1 Cross References

Identifier
PF09264

1 Found In

DB identifier Type Name
IPR011040 Domain Sialidases

1 GO Annotation

GO Term Gene Name
GO:0033691 IPR015344

1 Ontology Annotations

GO Term Gene Name
GO:0033691 IPR015344

1 Parent Features

DB identifier Type Name
IPR013320 Domain Concanavalin A-like lectin/glucanase domain

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15226294