Type: | Family | Name: | Monocarboxylate transporter 9 |
Description: | Monocarboxylate transporter 9 (MCT9), also known as SLC16A9, belongs to the MCT family. The function of MCT9 is not clear. A variant in human MCT9 gene has been linked to renal overload gout [].Monocarboxylate transporters (MCTs) catalyse the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane [, ]. All of the MCT family (also known as SLC16 solute carrier family) members share conserved sequence motifs. They are are predicted to have 12-transmembrane helices (TMs) with intracellular C and N termini and a large cytosolic loop between TMs 6 and 7 []. | Short Name: | MCT9 |