Protein Domain : IPR029898

Type:  Family Name:  Methionine adenosyltransferase 2 subunit beta
Description:  This entry represents the non-catalytic, regulatory beta subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyses the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. S-adenosylmethionine is the principal biological methyl donor [] and a key regulator of hepatocyte proliferation, death, and differentiation []. The beta subunit (MAT2B) regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition []. Short Name:  MAT2_B
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10491:SF2

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0048270 IPR029898
GO:0006556 IPR029898
GO:0048269 IPR029898

3 Ontology Annotations

GO Term Gene Name
GO:0048270 IPR029898
GO:0006556 IPR029898
GO:0048269 IPR029898

1 Parent Features

DB identifier Type Name
IPR005913 Family dTDP-4-dehydrorhamnose reductase family

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10644686
            17464973
            23539621