| Type: | Family | Name: | 2-aminoethylphosphonate ABC transporter system, permease protein phnU |
| Description: | The enzyme phosphonatase catalyses the degradation of 2-aminoethylphosphonate (AEP) in bacteria. This allows them to metabolise a range of organophosphonate compounds, including 2-aminoethylphosphonate, as a sole source of carbon, energy and phosphorus for growth []. The C-P bond in phosphonoacetaldehyde (Pald) is hydrolysed and a bi-covalent Lys53ethylenamine/Asp12 aspartylphosphate intermediate is formed []. This step can also be catalysed by C-P lyase [], with some bacteria having the genes for both pathways and some only for one of them. The 2-aminoethylphosphonate ABC transport system functions in the transport of 2-aminoethylphosphonate across the membrane for utilisation in the bacterial cell.phnU is probably part of the phnSTUV complex involved in 2-aminoethylphosphonate import. It is found in a region of the salmonella typhimurium LT2 genome [] responsible for the catabolism of 2-aminoethylphosphonate via the phnWX pathway (). | Short Name: | AminoethylPonate_ABC_perm-phnU |
