3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR009947 |
| GO:0042773 | IPR009947 |
| GO:0005743 | IPR009947 |
| Type: | Family | Name: | NADH:ubiquinone oxidoreductase subunit B14.5a |
| Description: | NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This family contains the eukaryotic NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a). This is approximately 100 residues long, and forms part of a multiprotein complex that resides on the inner mitochondrial membrane []. | Short Name: | NADH-UbQ_OxRdtase_B14.5a_su |
| GO Term | Gene Name |
|---|---|
| GO:0008137 | IPR009947 |
| GO:0042773 | IPR009947 |
| GO:0005743 | IPR009947 |
