3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0004198 | IPR029643 |
| GO:0005509 | IPR029643 |
| GO:0006508 | IPR029643 |
| Type: | Family | Name: | Calpain-1 |
| Description: | Calpain-1 catalytic subunit (CAPN1, also known as mu-calpain) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. The most abundant members of the calpain familiy are CAPN1 and CAPN2. They form heterodimers, which are regulated by a small regulatory subunit (28 kDa) encoded by the gene Capn4 []. Calpain-1 plays a role in regulating IgE-mediated mast cell activation []. Calpain-1 is also involved in mammary gland remodelling []. | Short Name: | CAPN1 |
| GO Term | Gene Name |
|---|---|
| GO:0004198 | IPR029643 |
| GO:0005509 | IPR029643 |
| GO:0006508 | IPR029643 |
