Type: | Family | Name: | Calpain-6 |
Description: | Calpain-6 (CAPN6) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. However, CAPN6 lacks the active-site cysteine residues, suggesting a loss of proteolytic activity. It is involved in regulating microtubule dynamics and actin reorganisation [, ]. CAPN6 may function as a suppressor of skeletal muscle differentiation []. | Short Name: | CAPN6 |