Protein Domain : IPR029540

Type:  Family Name:  Calpain-6
Description:  Calpain-6 (CAPN6) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. However, CAPN6 lacks the active-site cysteine residues, suggesting a loss of proteolytic activity. It is involved in regulating microtubule dynamics and actin reorganisation [, ]. CAPN6 may function as a suppressor of skeletal muscle differentiation []. Short Name:  CAPN6

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10183:SF281

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0051493 IPR029540

1 Ontology Annotations

GO Term Gene Name
GO:0051493 IPR029540

1 Parent Features

DB identifier Type Name
IPR022684 Family Peptidase C2, calpain family

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12843408
            24085852
            17210638
            23935533