Protein Domain : IPR020813

Type:  Conserved_site Name:  Fibrillarin, conserved site
Description:  Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (SnRNP), functioning in vivoin ribosomal RNA processing [, ]. It is associated with U3, U8 and U13 small nuclearRNAs in mammals [] and is similar to the yeast NOP1 protein []. Fibrillarin has awell conserved sequence of around 320 amino acids, and contains 3 domains, an N-terminal Gly/Arg-rich region; a central domain resembling other RNA-binding proteins and containing an RNP-2-like consensussequence; and a C-terminal alpha-helical domain. An evolutionarily related pre-rRNA processing protein, which lacks the Gly/Arg-rich domain, has been found in various archaebacteria.The signature pattern for this entry encompasses the RNP-2 like octapeptide sequence. Short Name:  Fibrillarin_CS

0 Child Features

0 Contains

1 Cross References

Identifier
PS00566

1 Found In

DB identifier Type Name
IPR000692 Family Fibrillarin

4 GO Annotations

GO Term Gene Name
GO:0003723 IPR020813
GO:0008168 IPR020813
GO:0006364 IPR020813
GO:0008033 IPR020813

4 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR020813
GO:0008168 IPR020813
GO:0006364 IPR020813
GO:0008033 IPR020813

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2686980
            2026646
            8493104