| Type: | Family | Name: | Fructose-bisphosphate aldolase class I, Gram positive bacteria-type |
| Description: | Fructose-bisphosphate aldolase () [, ] is a glycolytic enzyme that catalyses the reversible aldol cleavage or condensation of fructose-1,6-bisphosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate. There are two classes of fructose-bisphosphate aldolases with different catalytic mechanisms: class I enzymes [] do not require a metal ion, and are characterised by the formation of a Schiff base intermediate between a highly conserved active site lysine and a substrate carbonyl group, while the class II enzymes require an active-site divalent metal ion.This entry represents class I enzymes from Gram positive -and some Gram negative- bacteria. | Short Name: | FBA_I_Gram+-type |
