| Type: | Family | Name: | Actin cytoskeleton-regulatory complex protein Pan1, fungal |
| Description: | Pan1 is a component of the Pan1 actin cytoskeleton-regulatory complex (consists of Pan1, Sla1 and End3 in budding yeast) required for the internalization of endosomes during actin-coupled endocytosis []. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton []. It mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. It plays a role in the proper organisation of the cell membrane-associated actin cytoskeleton and promotes its destabilisation [, ]. | Short Name: | Pan1_fungal |
