1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR002877 | Domain | Ribosomal RNA methyltransferase FtsJ domain |
| Type: | Domain | Name: | RrmJ-type ribose 2-O-methyltransferase domain |
| Description: | This domain is found in cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1, which is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs []. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway []. This group also includes , which is thought to be inactive as it lacks the conserved Lys active site in position 367. | Short Name: | RrmJ-type_MeTrfase |
| DB identifier | Type | Name |
|---|---|---|
| IPR002877 | Domain | Ribosomal RNA methyltransferase FtsJ domain |
