Protein Domain : IPR030167

Type:  Family Name:  LIM domain-binding protein 1
Description:  LIM domain-binding protein 1 (LDB1) binds to the LIM domain of LIM homeodomain proteins which are transcriptional regulators. LDB1 is a multi-adaptor protein that mediates interactions between different classes of transcription factors and their co-regulators, and hence determine cell fate and differentiation []. In erythroid cells LDB1 is recruited to the beta-globin locus via LMO2 and is required for looping of the beta-globin locus control region (LCR) to the active beta-globin promoter []. Short Name:  LDB1
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10378:SF7

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0000989 IPR030167
GO:0030274 IPR030167
GO:0006357 IPR030167
GO:0005634 IPR030167

4 Ontology Annotations

GO Term Gene Name
GO:0000989 IPR030167
GO:0030274 IPR030167
GO:0006357 IPR030167
GO:0005634 IPR030167

1 Parent Features

DB identifier Type Name
IPR002691 Family LIM-domain binding protein

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            24874989
            14647207