Protein Domain : IPR024135

Type:  Family Name:  Hepatitis B X-interacting protein
Description:  Hepatitis B X-interacting protein (HBXIP) was originally recognised for its association with the X protein of hepatitis B virus (HBV) and ability to down-regulate HBV replication []. When complexed to the anti-apoptotic protein survivin, HBXIP interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerised APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway []. HBXIP is one of the Ragulator components that are required for mTORC1 activation by amino acids []. Short Name:  HBXIP
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PTHR13342
PR02092

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0019079 IPR024135
GO:0043066 IPR024135
GO:0043154 IPR024135
GO:0005737 IPR024135

4 Ontology Annotations

GO Term Gene Name
GO:0019079 IPR024135
GO:0043066 IPR024135
GO:0043154 IPR024135
GO:0005737 IPR024135

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            22980980
            12773388
            9499022