Protein Domain : IPR010138

Type:  Family Name:  UDP-2,3-diacylglucosamine hydrolase
Description:  This entry represents LpxH, or UDP-2,3-diacylglucosamine hydrolase (or diphosphatase), which is an essential enzyme in Escherichia colithat catalyses the fourth step in lipid A biosynthesis. This reaction involves pyrophosphate bond hydrolysis of the precursor UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate and UMP []. Several Gram-negative bacteria have homologues of LpxH and/or LpxH2, while others have only distant orthologues of LpxH or LpxH2, or lack these enzymes altogether []. Short Name:  UDP-diacylglucosamine_Hdrlase

0 Child Features

1 Contains

DB identifier Type Name
IPR004843 Domain Calcineurin-like phosphoesterase domain, apaH type

2 Cross Referencess

Identifier
TIGR01854
MF_00575

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016462 IPR010138
GO:0009245 IPR010138
GO:0005737 IPR010138

3 Ontology Annotations

GO Term Gene Name
GO:0016462 IPR010138
GO:0009245 IPR010138
GO:0005737 IPR010138

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12000771
            12000770