| Type: | Domain | Name: | Thiazole biosynthesis domain |
| Description: | The ThiI protein of Escherichia coli is a bifunctional protein in which most of the length of the protein is responsible for sulfurtransferase activity in 4-thiouridine modification to tRNA (). This rhodanese-like C-terminal domain, by itself, is able to synthesize the thiazole moiety during thiamin biosynthesis []. Note that the invariant Cys residue in this domain is unusual in being required for both activities of the bifunctional ThiI protein. | Short Name: | Thiazole_biosynth_dom |
