| Type: | Family | Name: | Putative condensing enzyme FabH-related |
| Description: | This family of proteins shows considerable homology and identical active site residues to FabH, the beta-ketoacyl-acyl carrier protein synthase III of bacteria and plants. The archaeal species in which it is found, however, do not have a readily detectable homologue of acyl carrier protein itself, suggesting the condensation of the acyl group with some other carrier. In Methanocaldococcus jannaschii(Methanococcus jannaschii) , Cys-112 is the site of acyl group attachment and His-234 and Asn-237 are also active site residues by homology to FabH.Closely related bacterial families include a polyketide antibiotic (2,4-diacetylphloroglucinol) biosynthesis protein from Pseudomonas fluorescensand an uncharacterised protein from Staphylococcus carnosus. | Short Name: | FabH-rel |
