Protein Domain : IPR028618

Type:  Family Name:  ATP-dependent RNA helicase DeaD
Description:  RNA helicases from the DEAD-box family are found in almost all organisms and have important roles in RNA metabolism, such as splicing, RNA transport,ribosome biogenesis, translation and RNA decay. They are enzymes that unwind double-stranded RNA molecules in an energy dependent fashion through thehydrolysis of NTP. DEAD-box RNA helicases belong to superfamily 2 (SF2) of helicases. As other SF1 and SF2 members they contain seven conserved motifswhich are characteristic of these two superfamilies [].DEAD-box is named after the amino acids of motif II or Walker B (Mg2+-binding aspartic acid). The RNA helicase DeaD is ATP-dependent [] and is induced by low temperatures []. In addition to its role in unwinding double stranded RNA, it is involved in ribosomal subunit biogenesis []. Short Name:  DEAD_helicase_DeaD

0 Child Features

0 Contains

1 Cross References

Identifier
MF_00964

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004004 IPR028618
GO:0000027 IPR028618
GO:0070417 IPR028618

3 Ontology Annotations

GO Term Gene Name
GO:0004004 IPR028618
GO:0000027 IPR028618
GO:0070417 IPR028618

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1531961
            8552679
            2045359
            15148362