Protein Domain : IPR014166

Type:  Family Name:  Tol-Pal system-associated acyl-CoA thioesterase
Description:  The tol-pal system consists of five critical genes. Inner membrane proteins TolQ and TolR convert proton motive force to energy that is transduced through TolA to an outer membrane complex of TolB and Pal. The system is known to be required to maintain outer membrane integrity. In a system with several homologous parts, ExbB and ExbD transduces energy through TonB to a variety of outer membrane proteins, many of which are siderophore receptors. The tol-pal system therefore may also be involved in transport. This family consists of a protein nearly always found in operons with the genes of the tol-pal system. The significance of this thioesterase to the tol-pal system is unclear, but either of two observations may be relevant. First, Pal, or peptidoglycan-associated lipoprotein, has a conserved N-terminal cleavage and acylation that makes it a lipoprotein. Second, the tol-pal system is implicated not only in the import of certain organics but also in the maintenance of outer membrane integrity (by an unknown mechanism) []. Short Name:  Tol-Pal_acyl-CoA_thioesterase

0 Child Features

2 Contains

DB identifier Type Name
IPR006683 Domain Thioesterase superfamily
IPR008272 Active_site 4-hydroxybenzoyl-CoA thioesterase, active site

1 Cross References

Identifier
TIGR02799

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0016790 IPR014166

1 Ontology Annotations

GO Term Gene Name
GO:0016790 IPR014166

1 Parent Features

DB identifier Type Name
IPR006684 Family Acyl-CoA thioester hydrolase YbgC/YbaW family

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16207916