Protein Domain : IPR030764

Type:  Family Name:  Solute carrier organic anion transporter family member 1C1
Description:  Solute carrier organic anion transporter family member 1C1 (SLCO1C1, also known as OATP1C1) belongs to the OATP family. It is a specific thyroid hormone transporter []. It mediates the transport of T4, rT3, T4 sulfate, estrone-3-sulfate (E1S), estradiol-17beta-glucuronide, and bromosulfophthalein. It is expressed in the Leydig cells of the testis and in brain capillaries in rat and mice, leading to the suggestion that Oatp1c1 is expressed at the blood-brain barrier []. The expression of SLCO1C1 and another key thyroid hormone transporter, MCT8, are regulated in a parallel manner during inflammation at the blood-brain barrier of rodents []. Short Name:  OATP1C1

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11388:SF18

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008514 IPR030764
GO:0015349 IPR030764
GO:0015711 IPR030764

3 Ontology Annotations

GO Term Gene Name
GO:0008514 IPR030764
GO:0015349 IPR030764
GO:0015711 IPR030764

1 Parent Features

DB identifier Type Name
IPR004156 Family Organic anion transporter polypeptide OATP

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            20660303
            18566113
            25594699