1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR013320 | Domain | Concanavalin A-like lectin/glucanase domain |
| Type: | Domain | Name: | Glycoside hydrolase, family 33, N-terminal |
| Description: | O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Sialidases () hydrolyse alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Sialidases may act as pathogenic factors in microbial infections [].The 1.8 A structure of trans-sialidase from leech (Macrobdella decora, ) in complex with 2-deoxy-2, 3-didehydro-NeuAc was solved. The refined model comprising residues 81-769 has a catalytic beta-propeller domain, a N-terminal lectin-like domain and an irregular beta-strandeddomain inserted into the catalytic domain []. | Short Name: | Glyco_hydro_33_N |
| DB identifier | Type | Name |
|---|---|---|
| IPR013320 | Domain | Concanavalin A-like lectin/glucanase domain |
