Type: | Family | Name: | Mycothione reductase |
Description: | Mycothiol, a glutathione analog in Mycobacterium tuberculosisand related species, can form a disulphide-linked dimer called mycothione. This enzyme can reduce mycothione to regenerate two mycothiol molecules. The enzyme shows some sequence similarity to glutathione-disulphide reductase, trypanothione-disulphide reductase, and dihydrolipoamide dehydrogenase. The characterised protein from M. tuberculosis, a homodimer, has one FAD cofactor per monomer, and uses NADPH as a substrate []. | Short Name: | Mycothione_reductase |