Protein Domain : IPR018456

Type:  Conserved_site Name:  PTR2 family proton/oligopeptide symporter, conserved site
Description:  The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The PTR family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of a number of recently discovered peptide transport proteins []. These proteins that seem to be mainly involved in the intake of small peptides with the concomitant uptake of a proton [].These integral membrane proteins are predicted to comprise twelve transmembrane regions.This entry describes two conserved sites. The first conserved site is found within a region that includes the end of the second transmembrane region, a cytoplasmic loop as well as the third transmembrane region. The second conserved site corresponds to the core of the fifth transmembrane region. Short Name:  PTR2_symporter_CS

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PS01022
PS01023

3 Found Ins

DB identifier Type Name
IPR020846 Domain Major facilitator superfamily domain
IPR000109 Family Proton-dependent oligopeptide transporter family
IPR005279 Family Dipeptide/tripeptide permease

3 GO Annotations

GO Term Gene Name
GO:0005215 IPR018456
GO:0006857 IPR018456
GO:0016020 IPR018456

3 Ontology Annotations

GO Term Gene Name
GO:0005215 IPR018456
GO:0006857 IPR018456
GO:0016020 IPR018456

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7476181
            7817396